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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
32.42
Human Site:
T422
Identified Species:
54.87
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
T422
H
N
L
I
D
T
T
T
S
M
H
S
V
E
V
Chimpanzee
Pan troglodytes
XP_520821
925
103112
T422
H
N
L
I
D
T
I
T
G
M
H
S
V
E
V
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
T403
H
N
L
I
D
T
I
T
G
M
H
S
V
E
V
Dog
Lupus familis
XP_543872
907
102087
T403
H
N
L
I
D
T
I
T
G
I
H
S
V
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
T374
H
N
L
I
D
T
I
T
N
I
H
S
T
E
V
Rat
Rattus norvegicus
XP_001070646
845
94905
M356
H
S
Q
L
L
Q
Y
M
E
R
Y
R
K
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
T430
H
N
L
I
D
T
I
T
A
I
H
S
A
E
V
Chicken
Gallus gallus
XP_416375
940
105739
T434
H
N
L
I
D
T
I
T
C
I
Y
S
A
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
S382
H
N
L
M
D
T
I
S
A
I
H
S
A
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
A360
H
N
L
L
D
S
V
A
Q
L
H
G
S
E
I
Honey Bee
Apis mellifera
XP_001121183
769
88327
L313
L
L
H
C
Y
N
Q
L
C
Q
Y
Q
K
R
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
S324
Q
L
L
Q
I
L
S
S
W
V
R
Q
L
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
N397
V
I
I
D
E
A
H
N
L
I
E
T
I
N
S
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
S512
H
N
I
M
D
A
V
S
N
V
H
A
A
E
I
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
86.6
86.6
80
N.A.
73.3
6.6
N.A.
73.3
66.6
N.A.
53.3
N.A.
40
0
N.A.
6.6
P-Site Similarity:
100
86.6
86.6
86.6
N.A.
86.6
33.3
N.A.
86.6
80
N.A.
86.6
N.A.
66.6
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
0
8
15
0
0
8
29
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
15
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
72
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
8
0
0
72
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
22
0
0
8
0
8
8
% G
% His:
79
0
8
0
0
0
8
0
0
0
65
0
0
0
0
% H
% Ile:
0
8
15
50
8
0
50
0
0
43
0
0
8
0
22
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% K
% Leu:
8
15
72
15
8
8
0
8
8
8
0
0
8
0
8
% L
% Met:
0
0
0
15
0
0
0
8
0
22
0
0
0
0
0
% M
% Asn:
0
72
0
0
0
8
0
8
15
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
8
0
8
8
0
8
8
0
15
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
8
8
0
15
0
% R
% Ser:
0
8
0
0
0
8
8
22
8
0
0
58
8
0
8
% S
% Thr:
0
0
0
0
0
58
8
50
0
0
0
8
8
0
0
% T
% Val:
8
0
0
0
0
0
15
0
0
15
0
0
29
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
22
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _